Blog · Medicines
Turmeric and Warfarin: Why the Pair Needs a Doctor
Turmeric and warfarin can be a risky pair. Memorial Sloan Kettering warns that turmeric may raise bleeding risk with warfarin and antiplatelet drugs. Synaptril contains a turmeric extract and also coenzyme Q10, which matters for warfarin too. If you take a blood thinner, ask your prescriber before using it.
Written by the Synaptril label deskUpdated · 4 min read

The warning01
Is it safe to take turmeric with warfarin?
It is not a safe assumption. Turmeric may add to the bleeding effect of warfarin, so it should only be taken with your prescriber's agreement.
Memorial Sloan Kettering lists a bleeding risk when turmeric is combined with warfarin or antiplatelet drugs (MSKCC, Turmeric). The evidence is mostly cautionary, but the stakes are high enough to ask first.
Warfarin is a narrow-margin drug. Small shifts in its effect can matter, which is why doctors check blood tests called INR readings.
A person on warfarin usually has a routine: the same dose, regular tests and steady habits. Adding a new supplement breaks that routine, and the clinic cannot adjust for something it does not know about.
The reason02
Why does turmeric matter for blood thinners?
Turmeric matters for blood thinners because curcumin may slow clotting. Two things that slow clotting together can push bleeding risk up.
The same caution covers antiplatelet medicines, which work in a different way but also reduce clotting (MSKCC, Turmeric). Bruising more easily, nosebleeds and bleeding gums are the early hints. Dark or tar-like stools and blood in the urine are more serious and need prompt care.
None of this means every person on warfarin who takes turmeric will bleed. It means nobody can promise they will not, and your clinic is the one place that can watch for it.
Turmeric also has a smaller kidney stone link in the same source. That is a separate point, but it adds to the list of questions for your doctor.
The honest summary is that the proof is thin and the caution is strong. A thin proof is not a green light when the other side is bleeding.
| Ingredient | Concern with warfarin |
|---|---|
| Turmeric extract | May raise bleeding risk |
| Coenzyme Q10 | May lessen warfarin's effect; INR checks advised |
| Magnesium glycinate | No clotting concern in our sources |
The capsules03
What does the Synaptril label say about medicines?
The Synaptril label says to consult a physician before use, especially if you take a medication or have a medical condition. It names no specific drug.
It also says not to exceed the recommended dose of one capsule a day. The turmeric amount is not printed, and our estimate is under about 44 mg per capsule (21 CFR 101.36, supplement labeling). A small amount is not a guarantee of safety on a narrow-margin drug.
The label also does not say whether the extract is a plain or a high-absorption form (NCCIH, Turmeric). Without that, nobody outside the company can say how much curcumin actually reaches the blood.
The supplements and medicines guide lists the other pairings worth checking.

Synaptril: from $49 a bottle30 capsules · 2, 3 or 6 bottles · free shipping on 3 or 6 · 60-day money-back guarantee
See packsYour check04
What should you ask before combining them?
Ask your prescriber or pharmacist whether any supplement with turmeric is acceptable for you. Bring the bottle and the Supplement Facts panel.
The quick check below covers the question that matters most here. It does not replace advice.
Keep taking prescribed medicine as directed. Never stop warfarin because of a supplement.
Bring three items to the appointment: the bottle, a photo of the Supplement Facts panel and a list of your other medicines. With those, a pharmacist can answer in a few minutes.
If you go ahead05
What if your doctor says it is fine?
If your doctor agrees, start with one capsule a day and tell the clinic so any blood tests are read with that in mind. Report new bruising right away.
Do not add other supplements at the same time. If something changes, you will want to know which product caused it.
The 60-day guarantee gives you time to decide, and you must return all bottles to use it. Return postage is paid by the buyer.
American Synaptril authorized shop
Ready to try Synaptril?
Start with a medicine check, then choose your pack. Three or six bottles cost less per bottle and ship free, and each pack comes with the 60-day money-back guarantee.
- Secure checkout
- 60-day money-back guarantee
- Ships from the U.S.

FAQ06
Blood thinner questions
How long before surgery should turmeric be stopped?
Many surgeons ask patients to stop turmeric and similar supplements ahead of an operation because of bleeding. The exact time varies, so tell the surgical team what you take.
Can I take Synaptril if I only use aspirin?
Aspirin is an antiplatelet drug, and Memorial Sloan Kettering lists that class with the turmeric bleeding caution. Ask your doctor before combining them, even at a low dose.
Does cooking with turmeric affect warfarin?
Normal food amounts are far lower than a capsule extract, and our sources focus on supplements. Keep your diet steady and mention any big change to your clinic.
Which bleeding signs should I report?
Report unusual bruising, bleeding gums, nosebleeds that will not stop, black stools or blood in urine. Severe bleeding or a head injury needs emergency care.
Who wrote this07
Written and reviewed by
Pages built from the label, the sales page and linked NIH, FDA, CDC, FTC and peer-reviewed sources.
Last updated . Read our editorial standards and how we check reviews. This website is run by an American Synaptril authorized shop, not by the manufacturer or the distributor. We earn money when you buy through our order links.
Keep reading
More about Synaptril
American Synaptril authorized shop
Ready to try Synaptril?
Start with a medicine check, then choose your pack. Three or six bottles cost less per bottle and ship free, and each pack comes with the 60-day money-back guarantee.
- Secure checkout
- 60-day money-back guarantee
- Ships from the U.S.

